100% Pure Watusi Ankole cattle are extremely rare worldwide. When the World Watusi Association was formed the decision was made to crossbreed the cattle to increase the gene pool and to more widely expose the breed to the public. To this end an upbreeding program was created as follows:
| FP Bull | NP Bull | |||
| FP cow | ♀♂ = FP | ♀♂ = NP | ||
| NP cow | ♀♂ = NP | ♀♂ = NP | ||
| ¾ blood cow | ♀ = NP | ♂ = ⅞ | ♀ = NP | ♂ = ⅞ |
| ½ blood cow | ♀♂ = ¾ | ♀♂ = ¾ | ||
| Grade cow/other | ♀♂ = ½ | N/A | ||